Post-Doc position in Department of Medical Biochemistry and Biophysics and MIMS Umeå University, Sweden
TOPIC: Visualization of endocytic carrier formation using advanced microscopy techniques
PROJECT DESCRIPTION:
The proposed research builds on previous biochemical and structural characterization of proteins involved in endocytosis, and further elaborates on the sequential recruitment of proteins, and dynamics of membrane remodelling phenomena. This project focuses on developing fluorescent tools and reagents for visualizing the dynamics and specificity of endocytic carrier formation using STORM and four-dimensional fluorescent microscopy.
For more details please contact:
Dr. Richard Lundmark
METHODS:
This study make use of advanced fluorescent live cell imaging using a Nikon A1R system, fully operational for TIRF and FRAP/FRET microscopy and equipped with micromanipulators for injection into individual cells. In addition the microscope system is combined with a STORM-unit for ultra resolution microscopy. Further techniques involve generation of stable cell lines, cell culture, and generation of fluorescent reagents, protein biochemistry, and standard cell /molecular biology techniques.
POSITION:
The position is available for the initial 2 years as a tax-exempt fellowship with a possibility of extension.
RELEVANT PUBLICATIONS:
Howes M, et al. Journal of Cell Biology, 2010. Lundmark R, et al. Current Biology 2008. Daumke O, et al. Nature 2007
LOCATION:
The department of Medical Biochemistry and Biophysics is located within the Chemical Biological Centre at Umeå University and provides well- equipped common facilities and excellent platforms for imaging and protein biochemistry in a creative, inspiring and highly interactive environment.
APPLICATION DETAILS FOR POST-DOC FELLOWSHIP:
We are looking for enthusiastic candidates who have a genuine interest in, and experience from, imaging techniques. The applicant should have received or be about to receive a Ph.D. in cell/molecular biology or a related discipline. Prior experience of fluorescent microscopy in active research lab will be an added advantage as well as experience of developing and handling novel fluorescent tools for imaging. The successful candidate is expected to design and execute his or her project independently but also work in close collaboration with the other members of the team.
Applicants should submit their:
· CV
· The names and contact details of three reference persons(preferably via email)
To
Dr. Richard Lundmark
DEADLINE FOR APPLICATION: September 30, 2011
FOR DETAILS, PLEASE REFER
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