Sandwich Placement at Sanger Institute

Sandwich Placement at Sanger Institute

Sandwich Year placements are available for students who are following a four year degree with a dedicated year for a work placement included in their course.

Placements are available for twelve months starting in the summer or autumn.

Placements are potentially available across the full spectrum of the Institute's activities however previous placements have included work that primarily falls within the following subject areas although work in other areas of the Institute may be considered if available:

• Virus Genomics
• Computer Science
• Genetics of deafness
• Genetics of Instinctive behaviour
• Parasite Genomics
• Malaria Interest group

These placements are limited in number and we cannot accommodate all requests. Applicants will be shortlisted to attend an interview based upon the merit of their application. You can find out more about the work of the Institute by visiting our research or scientific resources pages.

These short-term Placements are open to EU students or non-EU students who are studying at a UK university or who have the right to work in the UK.

Institute will pay you a salary of £15,364 per annum. This is subject to UK standard tax and National Insurance deductions. Contracted working hours are 37 hours per week. The Institute's normal working day is 9am - 5pm (4:30pm on Friday).

You will also be entitled to 25 days per annum paid holiday plus bank holidays.

Applications are invited from 28 November until 31 January each year and should be made using our on-line recruitment facility. To apply, visit Current jobs and look for Industrial Placement.

Shortlisted candidates will be invited for interview during March and early April.

If you are shortlisted for interview, you will need to provide a letter of recommendation from your Course Tutor.

Apply now on-line

FOR DETAILS, PLEASE REFER

https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=140665

Vacancy for Senior Scientific Manager( Infection & Immunology) at Wellcome Trust Sanger Institute

Wellcome Trust Sanger Institute

POST: Senior Scientific Manager - Infection & Immunology

SALARY RANGE: £36672 to £48459 dependent on experience

The Wellcome Trust Sanger Institute is looking for an exceptional individual with a strong scientific background and management capabilities to lead the Infection & Immunology, Haematology & Clinical Chemistry area, which is a major component of MGP phenotyping.

This newly created role will be responsible for managing the team and accountable for planning throughput and delivering the required phenotyping data to the research community.  The postholder will also play a critical role in ensuring that potential scientific outputs of the MGP can be realised by working with Sanger faculty and external collaborators to drive and support high quality scientific publications using phenotyping data.

Institute  offers a competitive reward package, including excellent benefits.

ESSENTIAL SKILLS

The postholder will be required to have specialist scientific knowledge and experience at PhD level in Mouse Genetics (or in an area of interest to the MGP including but not limited to immunology, haematology, infection, developmental biology, metabolic sciences, in life phenotyping) or equivalent extensive experience.  He/she will also require:

Significant postdoctoral level research experience using the mouse as a model organism

Evidence of the ability to successfully implement and manage complex plans for scientific programmes

Strong record of accomplishment managing technical/professional groups

Proven success working in a multidisciplinary team

Strong interpersonal skills with the ability to build good working relationships and team spirit

Strong computing use skills              

Proven ability to successfully manage collaborative projects

Proven track record of leading publications and presentation of outcomes of work in prestigious conferences

IDEAL SKILLS

Experience of working on mouse mutant programmes and a background of managing people in a high throughput environment are desirable.

OTHER INFORMATION

Informal enquiries may be made to Jacqui White (MGP Phenotyping Manager) – email: jkw@sanger.ac.uk  tel: 01223 495346 or David Adams (MGP Faculty-Lead) – email: da1@sanger.ac.uk

tel: 01223 834244.

CLOSING DATE 31ST DECEMBER 2011

Apply now on-line

FOR DETAILS, PLEASE REFER

https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=140370

Senior Scientific Manager( In Life Phenotyping) at Wellcome Trust Sanger Institute

Wellcome Trust Sanger Institute

POST: Senior Scientific Manager - In Life Phenotyping

SALARY RANGE: £36672 to £48459 dependent on experience

The Wellcome Trust Sanger Institute is looking for an exceptional individual with a strong scientific background and management capabilities to lead the In Life Phenotyping (Metabolism, Skeletal and Sensory) area, a major component of MGP phenotyping.

This newly created role will be responsible for managing the team and accountable for planning throughput and delivering the required phenotyping data to the research community.  The postholder will also play a critical role in ensuring that potential scientific outputs of the MGP can be realised by working with Sanger faculty and external collaborators to drive and support high quality scientific publications using phenotyping data.

Institute offers a competitive reward package, including excellent benefits.

ESSENTIAL SKILLS

The postholder will be required to have specialist scientific knowledge and experience at PhD level in Mouse Genetics (or in an area of interest to the MGP including but not limited to immunology, haematology, infection, developmental biology, metabolic sciences, in life phenotyping) or equivalent extensive experience.  He/she will also require:

Significant postdoctoral level research experience using the mouse as a model organism

Evidence of the ability to successfully implement and manage complex plans for scientific programmes

Strong record of accomplishment managing technical/professional groups

Proven success working in a multidisciplinary team

Strong interpersonal skills with the ability to build good working relationships and team spirit

Strong computing use skills             

Proven ability to successfully manage collaborative projects

Proven track record of leading publications and presentation of outcomes of work in prestigious conferences

IDEAL SKILLS

Experience of working on mouse mutant programmes and a background of managing people in a high throughput environment are desirable.

OTHER INFORMATION

Informal enquiries may be made to Jacqui White (MGP Phenotyping Manager) – email: jkw@sanger.ac.uk  tel: 01223 495346 or David Adams (MGP Faculty-Lead) – email: da1@sanger.ac.uk

 tel: 01223 834244.

CLOSING DATE 31ST DECEMBER 2011

FOR DETAILS, PLEASE REFER

https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=140368

Recruitment of Senior Scientific Manager - Developmental Biology at Wellcome Trust Sanger Institute

Wellcome Trust Sanger Institute

POST: Senior Scientific Manager - Developmental Biology

SALARY RANGE: £36672 to £48459 dependent on experience

The Wellcome Trust Sanger Institute  is looking for an exceptional individual with a strong scientific background and management capabilities to lead the Developmental Biology area, a major component of MGP phenotyping.

This newly created role will be responsible for managing the team and accountable for planning throughput and delivering the required phenotyping data to the research community.  The postholder will also play a critical role in ensuring that potential scientific outputs of the MGP can be realised by working with Sanger faculty and external collaborators to drive and support high quality scientific publications using phenotyping data.

Institute offers a competitive reward package, including excellent benefits.

ESSENTIAL SKILLS

The postholder will be required to have specialist scientific knowledge and experience at PhD level in Mouse Genetics (or in an area of interest to the MGP including but not limited to immunology, haematology, infection, developmental biology, metabolic sciences, in life phenotyping) or equivalent extensive experience.  He/she will also require:

Significant postdoctoral level research experience using the mouse as a model organism

Evidence of the ability to successfully implement and manage complex plans for scientific programmes

Strong record of accomplishment managing technical/professional groups

Proven success working in a multidisciplinary team

Strong interpersonal skills with the ability to build good working relationships and team spirit

Strong computing use skills             

Proven ability to successfully manage collaborative projects

Proven track record of leading publications and presentation of outcomes of work in prestigious conferences

Ideal Skills

Experience of working on mouse mutant programmes and a background of managing people in a high throughput environment are desirable.

OTHER INFORMATION

Informal enquiries may be made to Jacqui White (MGP Phenotyping Manager) – email: jkw@sanger.ac.uk tel: 01223 495346 or David Adams (MGP Faculty-Lead) – email: da1@sanger.ac.uk tel: 01223 834244.

CLOSING DATE 31ST DECEMBER 2011

Apply now on-line

FOR DETAILS, PLEASE REFER

https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=140367

Recruitment of Head of Operations( Stem Cells and Cellular Phenotyping Facility)at Wellcome Trust Sanger Institute

Wellcome Trust Sanger Institute

POST: Head of Operations, Stem Cells and Cellular Phenotyping Facility

CLOSING DATE: 6th January 2012

The Wellcome Trust Sanger Institute, based south of Cambridge  islooking for a Head of Operations with an excellent track record of operational scientific, project & people management to work with the Senior Management Team to set up and ultimately run this important new high throughput facility.  You will be totally accountable for the operational delivery of the services provided and ensuring that these meet customer requirements.  These will encompass: sample reception, transduction, derivation, differentiation, informatics and cellular phenotyping.  Once implemented this fully operational pipeline will support new lines of scientific enquiry by allowing us to assess the impact of genetic variation at a cellular level in health and disease.

Working alongside the Senior Management Team you will contribute towards the delivery of the overall stem cell and cellular phenotyping strategy, collaborating with customers to understand the scientific needs of the programme and forecast future demand.

This is a fantastic opportunity to lead and deliver services at the forefront of science and technology with the potential for significant scientific advances and health impacts. We offer a competitive reward package [base salary from £60k], including excellent benefits and relocation support.

ESSENTIAL SKILLS

·         Demonstrable success in delivering a large number of highly complex projects through others on time, in budget and to agreed quality standards.

·         Significant experience in an operational scientific management role

·         Experience in determining and establishing KPI’s, SLA’s

·         Experience of successfully resolving a range of people related issues effectively involving formal mechanisms

·         Highly developed communication skills with experience of dealing with people at all levels successfully

·         High level of influencing and negotiating skills

·         Excellent Relationship builder

·         Demonstrable leadership skills

·         Strong people management skills and ability to manage a large diverse team

·         Demonstrable evidence of coaching managers successfully

·         Proven organisational skills with the ability to plan and schedule effectively.

·         Proven ability to be able to deliver customer specifications

·         Strategic thinking skills, ability to see the ‘bigger picture’

·         Experience of working in a constantly changing environment with the ability to interpret management information to amend plans

·         Experience in successfully managing significant change

·         Work independently

·         Complex problem solver

·         Skills in financial management, budget and resources

·         Familiarity with Regulatory requirements for Human samples/tissue

IDEAL SKILLS

·         Experience in operational management involving, tissue culture, liquid handling robotics, analytical equipment, imaging equipment, LIMs and containment requirements

·         Familiarity with specific scientific terminology and application

·         Knowledge and experience of cell biology

·         PhD in biological science; background in life sciences

OTHER INFORMATION

Please submit a CV and a covering letter with the application. Informal enquiries may be made to Emma Millican, Head of DNA Pipelines – email: em8@sanger.ac.uk tel: 01223 492388

Apply now on-line

FOR DETAILS, PLEASE REFER https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=139931

Faculty Positions in Stem Cells and Cellular Phenotyping Programme at Sanger Institute

Wellcome Trust Sanger Institute

Faculty Positions in our new Stem Cells and Cellular Phenotyping Programme

The Wellcome Trust Sanger Institute, based south of Cambridge, is one of the world’s leading genomic research centres funded primarily by the Wellcome Trust. Our mission is to use genome sequences to advance understanding of the biology of humans and pathogens in order to improve human health.

The Institute conducts research in four thematic areas – human genetics, pathogen genetics, model organism genetics and informatics. Building on its expertise in the genetic manipulation of ES cells and the production of iPS cells, we are developing plans for a new scientific programme in stem cells and cellular phenotyping [SCCP]. The programme will have two major components – a resource of stem cells/iPS cells and a high-throughput cellular phenotyping platform. The new platform will sit alongside our established large scale experimental pipelines as part of an extensive scientific infrastructure including sequencing, genotyping, sample management, large scale PCR and others which support and drive numerous projects both internally and externally.

Scientific leadership, technical expertise and operational excellence will be needed to realise the vision of this high profile strategic initiative and we therefore wish to bring the best possible team together.  We will be recruiting at a number of levels during the coming months – faculty, technology experts and senior operational managers.  Our initial focus is on establishing the complex infrastructure and implementing a fully operational pipeline. This in turn will bring scientific opportunities and new lines of enquiry by allowing us to assess the impact of genetic variation at the cellular level in health and disease.

We are seeking outstanding scientists with interests in reprogramming of cells to iPS cells, differentiating pluripotent cells to somatic tissues and/or engineering of stem cells.  Individuals with broad interests in these technologies and their application to the development of cellular models are encouraged to apply.

Applications are invited from scientists at different career stages – from first faculty position (CDF Group Leader or Group Leader - salary from £45,000) to senior PIs with a significant track record of successful independent research (Senior Group Leader – salary from £65,000). We also offer excellent benefits and relocation support. Applications from women, who are under-represented in our Faculty, are particularly encouraged, although we welcome approaches from any scientists with relevant research interests.

For further information on the Sanger faculty model go to  http://www.sanger.ac.uk/workstudy/career/faculty/

General enquiries can be directed to facultysearch@sanger.ac.uk

For informal discussion, contact Mike Stratton mrs@sanger.ac.uk

Applications should only be made through our on-line recruitment facility https://jobs.sanger.ac.uk/

 accompanied by:

Curriculum vitae, complete list of publications and details of three referees;

A two page description summarising scientific achievements to date; and A three page outline of future research plans indicating how these fit with, contribute to and make use of Sanger programmes and infrastructure.

Closing date for applications: 6th January 2012

FOR DETAILS, PLEASE REFER

https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=140423

Postdoctoral Fellow( Genetics of Immunity) at Sanger Institute

WELLCOME TRUST SANGER INSTITUTE

POST: Postdoctoral Fellow: Genetics of Immunity

SALARY RANGE: £28,280 to £34,778 per annum dependent on experience. This position is fixed-term for 3 years.

 CLOSING DATE: 31 December 2011.

Dr. Jeffrey Barrett's group at the Sanger Institute is looking for a Postdoctoral Fellow to lead a research project on the genetics of auto-immune, inflammatory, and infectious diseases, beginning with analysis of genome-wide association studies of:

1. 2000 cases of sickle cell disease with detailed quantitative phenotypes (collaboration with Julie Makani, Dar es Salaam)

2. Over 10,000 cases of severe malaria from the MalariaGEN consortium (collaboration with Dominic Kwiatkowski and Chris Spencer, Oxford)

3. 5000 cases of Tuberculosis infection in Russia (collaboration with Sergey Nejentsev, Cambridge)

4. 1000 cases of HIV infection in Africa (collaboration with Fred Vannberg and Manj Sandhu)

All of these studies are among the largest genetic studies of these diseases in the world, and their analysis will be integrated into the group's ongoing work on the genetics of auto-immune and inflammatory diseases in European samples. The project aims to explore models of risk variants across this spectrum of diseases in order to better understand their shared and distinct biology.

The fellow would then have scope to further develop the project in one of two ways dependent on their interest and experience. In either case they would have access to the additional strengths of the Sanger Institute in statistical genetics and functional biology:

1. More detailed statistical analysis of these data, for instance via Bayesian model comparisons or development of association tests which account for the substantial genetic heterogeneity in African populations.

2. Functional follow-up for genes identified via GWAS, e.g. gene expression in relevant white blood cell types, or collaboration with the mouse knockout and pathogen challenge labs at Sanger to directly test hypotheses about genetic function in infection.

The Sanger Institute is committed to capacity building for researchers at our partner institution in Africa, and the successful applicant would have the opportunity to spend time at collaborating sites to conduct research, help with training, and exchange expertise with local scientists. This role will require a committed researcher who enjoys scientific problem solving, and offers the opportunity for participation in both personally driven research and collaborative projects at the forefront of genomic science.

ESSENTIAL SKILLS

PhD in a relevant subject, such as molecular or statistical genetics, statistics, computer science, or medicine.

Significant practical experience with large-scale computational analysis.

Applied statistical knowledge.

Demonstrated track record in strong analytical skills, finding enjoyment and satisfaction in solving difficult problems.

Proven ability to work independently.

Effective written and oral communication and proven ability to work in a collaborative environment.

Established publication track record.

Demonstrable experience with scripting or programming (e.g. R, Perl, Python).

IDEAL SKILLS

Experience in human genetics, especially work on immunity-mediated disease. 

Experience working with large scale GWAS and/or next-generation sequence datasets.

Strong computer programming experience, including demonstrated aptitude with either scripting languages (e.g. Perl, Python) or compiled languages (e.g. C, Java).

OTHER INFORMATION

Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training. Successful applicant(s) who have submitted their PhD thesis and are awaiting their PhD award to be confirmed will initially receive a salary of £26103 pa. On confirmation of their PhD award applicants will be moved on to the pay scale above. 

The Barrett lab is focused on using next generation genomic technology, especially high throughput sequencing, to better understand the genetics of complex disease, especially auto-immune and infectious diseases.

See also: http://www.sanger.ac.uk/research/projects/statisticalcomputationalgenetics/

The closing date for applications is 31 December 2011

FOR DETAILS, PLEASE REFER

https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=139714

Research Assistant [Phenotyping]post at Wellcome Trust Sanger Institute

WELLCOME TRUST SANGER INSTITUTE

POST: Research Assistant [Phenotyping]

SALARY RANGE: £16892 to £21537 pa dependent on experience

The Wellcome Trust Sanger Institute is looking to recruit an enthusiastic and resourceful Research Assistant to join our exciting programme of research. The day to day activities of the role focus on characterising the mice generated by the Mouse Genetics Project, using a broad range of phenotyping assays and histological techniques designed to identify metabolic, cardiovascular, sensory and behavioural abnormalities. Detailed record keeping is required, as is contribution to data analysis, review and reporting.

ESSENTIAL SKILLS

The successful candidates will hold a BSc or have equivalent experience in the biological sciences. Applicants must be team oriented, highly organised with strong attention to detail and possess good communication skills.

IDEAL SKILLS

Experience of handling mice and using databases for data tracking would be advantageous.

OTHER INFORMATION

The Mouse Genetics Project is undertaking an extensive sequence/phenotype driven mutagenesis screen using the resources generated by the Wellcome Trust Sanger Institute as part of international efforts aimed at mutating over 95 percent of known mouse genes in embryonic stem cells. The mice generated by the programme will be made freely available to the scientific community. All mutant mouse lines generated at the Wellcome Trust Sanger Institute will be examined using a common battery of phenotyping tools and the data published on the web. The intention is to associate the loss of gene function with disease processes and developmental abnormalities.

This is a fixed-term maternity cover position and will continue until the postholder returns to work after her period of maternity leave. Due to the nature of the contract no minimum or maximum period of employment can be guaranteed. The maximum period of maternity leave available to our employees is 12 months.

The closing date for applicaitons is 6 January 2012

FOR DETAILS, PLEASE REFER

https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=140648

Postdoctoral Research Fellow ( Parasitic helminth genomics) position at Wellcome Trust Sanger Institute

WELLCOME TRUST SANGER INSTITUTE

POST: Postdoctoral Research Fellow (Parasitic helminth genomics)

SALARY RANGE: £28280 to £34778 dependent on experience.

CLOSING DATE: 22nd January 2012

Wellcome trust Sanger institute is seeking to recruit enthusiastic and ambitious postdoctoral fellows in three areas:

DESCRIPTION:

POSTDOCTORAL FELLOW - PARASITIC HELMINTH GENOMICS

You will contribute to a range of projects involving the application of very-high-throughput sequencing technologies to understand the biology of helminths. Existing projects build on genome sequence data to address scientific questions that span from population genomics through to functional genomics and immunology, and include working on a range of nematodes, flukes and tapeworms in collaboration with external experts in particular systems. Key aspects of this role will include the analysis of ‘next generation sequencing’ data, genome assembly and comparison, phylogenetics, population genetics, and analyzing transcriptome data, with the exact mix of projects and approaches depending on the interests and expertise of the successful candidate.

POSTDOCTORAL FELLOW - PARASITE FUNCTIONAL GENOMICS

You will develop functional genomics projects across neglected parasite species.   A major focus will be the analysis of gene expression throughout the life cycle of African trypanosomes. Using whole transcriptome sequencing (RNAseq), you will explore differences across the life cycle, for instance between bloodstream and late stage (central nervous system) forms. You will need to be an excellent communicator and work effectively with collaborators.  Key aspects of this role will include the analysis of ‘next generation sequencing’ data, especially  transcriptome data.  The role may involve some lab work depending on the interests and expertise of the successful candidate.

POSTDOCTORAL FELLOW - HELMINTH GENOMICS R&D

You will develop challenging new methodology to exploit sequencing approaches to investigating genome function for parasitic helminths.  Key areas will include genome sequencing from small, precious or unusual samples, and developing novel functional genomics approaches. This position will be laboratory-based, working in the context of the spectrum of the Sanger Institute’s R&D activities.

ESSENTIAL SKILLS

For the computer based role(s) you will need to have a PhD and either a strong background in bioinformatics, or a strong background in biology (especially parasitology) matched with some experience in bioinformatics, including simple scripting (e.g. Perl/Python) and statistical analyses (e.g. R package).  For the lab based role, you will need to have a PhD and a strong background in molecular biology, ideally with experience using next generation sequencing based approaches.  Familiarity with parasitology would be beneficial.

 OTHER INFORMATION

Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training.

Successful applicant(s) who have submitted their PhD thesis and are awaiting their PhD award to be confirmed will be placed on a transitional pay point, currently £26103. On confirmation applicants will be moved on to the pay scale above

The Wellcome Trust funded positions are offered on a 3-year contract, starting early 2012.

FOR DETAILS, PLEASE REFER

https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=140721

Senior Bioinformatician(Pathogen Informatics) at Wellcome Trust Sanger Institute

Wellcome Trust Sanger Institute

CURRENT JOB TITLE:Senior Bioinformatician – Pathogen Informatics

SALARY RANGE: £27316 to £37690 per annum dependent on experience.

CLOSING DATE: 8th January 2012

ROLE PROFILE REFERENCE [FOR HR USE ONLY]:133-16

REPORTS TO [NAME AND JOB TITLE]:Senior Scientific Manager, Pathogen Informatics

TEAM NO:Helminth Genome Improvement

MANAGEMENT RESPONSIBILITY FOR:None

INTERACTS WITH: WHO (TEAMS/PEOPLE/ORGANISATIONS): Own team members

Pathogen informatics: Scientific managers (Helminth genome improvemt & pathogen informatics)

Sequencing Informatics teams

Pathogen Genomics scientists

Purpose of the interaction: Identify and discuss requirements. Exchange ideas; provide support for complex computational tasks. Coordinate activities of other bioinformaticians in team. Influence, give/obtain knowledge and advice.

Co-develop solutions and avoid duplication of effort. Discuss developments and provide updates and ideas.

Software testing.

Agree to development and analysis tasks, inform on and evaluate progress.

Keep up to date with approaches and techniques. Identify and agree short-term targets.

Gather use-case observations and requirements and feedback to developers.

Understand user requirements and ensure that the software meets them; and that the scientists know how to use the software.

ROLE PURPOSE AND PRIMARY OBJECTIVE:

Work within the genome improvement team and in collaboration with the pathogen informatics team, developing bioinformatics pipelines and providing and coordinating computational support to process sequencing data for genome improvement

CORE ACCOUNTABILITIES [IN APPROXIMATE ORDER OF IMPORTANCE TO ROLE PURPOSE]:

1. Troubleshoot complex data-processing or software-related problems within the helminth genome improvement group

2. Identify realistic requirements for new software and work, with developers in the Pathogen Informatics team, on their design and implementation or contribute to existing software by extending or modifying standard pipelines and systems where appropriate

3. Perform bespoke analyses of new data types and develop software and provide training so that other members of the group can subsequently carry out similar analyses

4. Participate in the development of novel bioinformatics software tools and techniques for genome improvement

5. Regularly interact with scientific staff to assess results and troubleshoot problems

6. Plan, organise and execute own work, and oversee the work of more junior bioinformaticians, within projects of varying sizes to meet agreed, standards, objectives and deadlines

7. Document protocols and provide guidance to allow genome analysts to correctly use and have a good understanding of the potential (and limitations) of assembly-related tools

8. Present data to wide ranging audiences (including contributions to publications) for information exchange and to demonstrate the progress and impact of own work

9.Maintain relevant knowledge of the literatures, internet forums, etc and research, innovate and evaluate different methods / tools to determine the best and most up to date approaches to solving problems faced in genome improvement

10.Contribute to papers and posters to communicate work to internal and external scientific audiences to contribute to the national and international scientific enterprise

Most complex/challenging aspects of the role: Balancing the complex requirements for software analysis solutions against the limited programmer resources to find effective yet efficient solutions

KNOWLEDGE, SKILLS AND EXPERIENCE REQUIRED:

ESSENTIAL: PhD (or MSc plus extensive practical experience) in bioinformatics or a related area

Significant demonstrable experience in bioinformatics

Experienced Perl or Python programmer

Knowledge and experience of UNIX / LINUX on an advanced level

Experience of dealing with large data sets and running software on a compute farm

Good theoretical knowledge of DNA & RNA bioinformatics

Good theoretical knowledge of DNA structure and organisation

Highly developed problem solving skills

Possess a keen attention to detail

Ability to work effectively within a team, contributing to discussions and disseminating knowledge and information

Ability to effectively communicate at all levels, including appropriate formal or informal presentations

Ability to develop and maintain good working relationships both within and outside a team

DESIRABLE: Experience of training and supervising other team members

Experience with processing next-generation sequencing data

Practical knowledge and experience of relational databases

Knowledge of parasitology

Working knowledge of molecular biology

Good theoretical knowledge of common molecular biological approaches incl. cloning & DNA manipulation

Apply now on-line

FOR DETAILS, PLEASE REFER

 https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=139979

Postdoctoral Fellow( Systems Biology of Bone) position at Sanger Institute

Sanger Institute

POST: Postdoctoral Fellow: Systems Biology of Bone

SALARY RANGE: £28,280 to £34,778 per annum dependent on experience.

Seeking a highly motivated Postdoctoral Fellow to carry out fundamental research in Dr. Vijay Yadav's team on the factors that regulate bone mass, including the study of new mouse models of bone abnormalities; investigating the changes in endocrine systems and identifying the mechanisms involved. The role will involve evaluating large quantitites of genetic data to enhance the understanding of skeletal disorders and applying these novel insights to plan the next generation of studies of disease genetics.

The Sanger Institute is a world leader in large-scale genome sequencing, informatics and the production of animal models to study gene function; providing the successful candidate with excellent resources and a stimulating research environment. There is a commitment to personal and professional development in the group, and the successful applicant will be encouraged to develop their own ideas, drive their research project and establish a strong academic profile.

ESSENTIAL SKILLS

The successful candidate will have specific expertise in molecular genetic techniques, with the relevant knowledge of computational tools and a strong background in mouse or human molecular genetics with a Ph.D. in molecular biology or bone biology. In depth knowledge of specific aspects of mouse genetics and endocrine systems is essential as is an established track record of first author publications in peer reviewed journals.

IDEAL SKILLS

Previous experience in mouse genetics is essential, and cell culture experience is desirable. The candidate should display that they have the ability to work in a team and to organise their own work and the work of others. A more detailed description of required skills and experience is outlined in the role profile.

OTHER INFORMATION

Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training. Successful applicant(s) who have submitted their PhD thesis and are awaiting their PhD award to be confirmed will be placed on a transitional pay point, currently £26,103. On confirmation applicants will be moved on to the pay range above.

The Systems Biology of Bone Group studies the genes and gene networks that regulate bone cell functions using mice as model organisms. Their long-term aim is to identify therapeutic targets for treating bone abnormalities. For informal inquiries about the position please contact Vijay Yadav (vy1@sanger.ac.uk ) and additional information about the Group can be found at http://www.sanger.ac.uk/research/projects/bonesystemsbiology/

This is a 3 year fixed-term position.

FOR DETAILS, PLEASE REFER

 https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=141144