Postdoc(Plant Pathway Discovery at the Novo Nordisk Foundation, Center for Biosustainability) at University of Copenhagen

University of Copenhagen

Postdoc within Plant Pathway Discovery at the Novo Nordisk Foundation Center for Biosustainability

We are inviting applications for a position as postdoc within the project "Discovery of biosynthetic routes to pharmaceutically interesting diterpenoids in plants". The postdoc will be part of the founding team of the Section for Plant Pathway Discovery of the Novo Nordisk Foundation Center for Biosustainability (CFB).

The section is focused on the elucidation and characterisation of plant biosynthetic pathways with special interest in the identification of diterpenoid synthases and cytochromes P450. The work will be tightly integrated with the research groups in the CFB working with intelligent design of cell factories, the overall aim being to obtain biosustainable production of the diterpenoids. The position is available from 1 January 2012 or as soon as possible thereafter and for two years with the possibility for extension.

The successful applicant will work in a highly active international research environment at the Plant Biochemistry Laboratory, Department of Plant Biology and Biotechnology, University of Copenhagen (http://www.plbio.life.ku.dk/english.aspx ) and in close collaboration with other research groups at the CFB (http://www.biosustain.dtu.dk/ ).

DUTIES

The candidate will be responsible for elucidation of the pathways for synthesis of diterpenoids in medicinal plants with a focus on pharmaceutically active compounds. The position will include teaching and supervision of students to a limited extent.

QUALIFICATIONS - SELECTION CRITERIA

Applicants must have a PhD degree or similar qualifications in molecular biology, biochemistry, bioengineering, or microbiology. Qualifications within one or more of the following scientific areas are required:

Bioinformatics of next-generation sequence data.

Heterologous expression in microbes.

Analytical chemistry (LC-MS, GC-MS).

Membrane proteins.

Terpenoid biochemistry.

The candidate is also required to have good communication skills, to be enterprising and to possess good interpersonal skills.

QUALIFICATIONS

MANDATORY REQUIREMENTS:

·         PhD degree or equivalent in relevant field.

·         High quality publication record within PhD research field.

·         Strong work ethics, independent research record, and motivation to succeed within this highly competitive research field.

Preference will be given to candidates with:

·         Training from internationally leading research laboratories.

·         Experience with de novo assembly of 454/illumina data and data mining.

·         Experience with enzymes of the cytochromes P450 or terpene synthase families.

·         Background in organic or analytical chemistry.

·         Experience with bioreactor technology.

TERMS OF EMPLOYMENT

The post will be filled according to the Agreement between the Danish Ministry of Finance and the Danish Confederation of Professional Associations. The post is covered by the Protocol on Job Structure.

Applications will be assessed according to the Ministry of Science Technology and Innovation Executive Order no 284 of 25. April 2008. Read more about the recruitment process at LIFE here.

The University of Copenhagen welcomes applications from suitably qualified candidates regardless of age, gender, race, religion or ethnic background.

Questions

For further information about the post, please contact Professor Birger Lindberg Møller +45 3533 3707 or Björn Hamberger +45 3533 3328 (bjoernh@life.ku.dk ).

You can read more about the Novo Nordisk Foundation Center for Biosustainability on http://www.biosustain.dtu.dk/ .

Potential applicants from outside Denmark will find information about life in Denmark (taxation, healthcare etc) at http://ism.ku.dk/

APPLICATION

Apply by clicking "Apply online" below.

Applications - in English - must include:

Cover letter

CV with documentation of education

A complete list of publications

A maximum of 10 relevant scientific works which the applicant wishes to be included in the assessment

Statement outlining the applicant´s most important research contributions (2-4 pp)

Documentation for additional research qualifications

Contact information of referees

Teaching portfolio

Participation in development of educations and seminars

Development of educational material

Experience with examination and/or censorship

Please submit your application no later than 31 December 2011

Only electronic applications are accepteed.

Apply online

Deadline: 31-12-2011

FOR DETAILS, PLEASE REFER http://www.ku.dk/english/available_positions/vip/

Ph.D Scholarship(Implications of charges in lipid membrane curvature induced by β-Arrestins ) at University of Copenhagen

PHD SCHOLARSHIP: Implications of charges in lipid membrane curvature induced by β-Arrestins 

Department of Basic Sciences and Environment, Faculty of Life Sciences at University of Copenhagen is offering a PhD scholarship commencing 15 January 2012 or soon thereafter. The application deadline is 31 December 2011.

PROJECT DESCRIPTION

The PhD project is within the area of membrane biophysical chemistry studying different binding mechanisms into the cell. The membrane spanning G-protein coupling receptors (GPCR) facilitate crucial physiological responses to a variety of extracellular ligands such as hormones neurotransmitters, ions, photons and other stimuli, thus 50% of drugs available in the market today target GPCR. The biological mechanism behind the signaling is believed to involve several other biomolecules. For instance, b-Arrestins are proteins thought to turn off receptor signaling by assisting the recruitment of Clathrin leading to endocytosis of GPCRs, where the receptor is removed from the plasma membrane and the activating extracellular ligand. b-Arrestin was found to bind onto membranes containing phosphatidylinositol trisphosphate, PI(3,4,5)P3-lipids. We have recently shown that such binding is lipid specific and not driven by for instance the lipid charge. These experiments revealed a novel function of b-Arrestin that maybe critically contributing in the endocutosis of GPCRs.

Here we propose to characterize the interaction of b-Arrestin with lipid membranes using a combination of powerful and complementary biophysical characterization techniques. Using neutron scattering and reflectometry we will characterize the molecular structure of lipid membranes upon b-Arrestin binding to lipid membranes containing PI(3,5,5)P3-lipids. Using fluorescence microscopy we will characterize the kinetics and association energy of the protein with membranes of different composition and curvature. Using Atomic force microscopy and cryo-TEM we will characterize the lateral packing arrangement of the protein. Understanding how b-Arrestins interact with membranes is expected to reveal a bilayer-mediated contribution to the endocytosis of GPCRs.

The project involves collaboration with research partners at U.C. including Professors D. Stamou, M. Cárdenas, and Kell Mortensen, and Prof. R. Sunahara at University of Michigan.

Principal supervisor:

Professor Kell Mortensen

Department of Basic Sciences and Environment, University of Copenhagen

E-mail: kell@life.ku.dk

Co-supervisors:

Associate Prof. Marité Cárdenas Gómez

Department of Chemistry, University of Copenhagen

E-mail: cardenas@nano.ku.dk

Prof. Dimitrios Stamou

Department of Neuroscience and Pharmacology, University of Copenhagen

E-mail: stamou@nano.ku.dk

JOB DESCRIPTION

Your key tasks as a PhD fellow at LIFE are:

Manage and carry through your research project

Take PhD courses

Write scientific articles and your PhD thesis

Participate in international congresses

Stay at a research institution abroad for a few months

Teach and disseminate your research

QUALIFICATIONS

We seek a talented and dedicated student with

A Masters degree of relevance to the project (chemistry, biochemistry, biophysics, biology or similar)

The candidate should further have some experience/in depth knowledge in at least one of the techniques below:

Scattering techniques

Surface sensitive techniques

Biomembranes

FORMAL REQUIREMENTS

The successful applicant of the PhD scholarship must pass an enrolment in the LIFE Graduate School before the Faculty can finish the letter of employment.

Graduate School of Faculty of Life Sciences, LIFE strives to give our students the best international career prospects within our main research areas.

TERMS OF EMPLOYMENT

The position will be filled according to the agreement between the Danish Ministry of Finance and the Danish Confederation of Professional Associations. The post is covered by the Protocol on Job Structure.

APPLICATION PROCEDURE

Apply by clicking "Apply online" below.

Applications - in English - must include:

·         Cover Letter, stating which PhD project you are applying for and detailing your motivation and background for applying for the specific PhD project.

·         CV

·         Diploma and transcripts of records 

·         Other information for consideration, e.g. list of publications (if any), peer reviewed and other

·         Personal Recommendations  

A maximum of 3 relevant scientific works which the applicant wishes to be included in the assessment.

The applicant will be assessed according to the Ministry of Science Technology and Innovation Executive Order no 284 of 25. April 2008.

By the end of January 2012, all applicants will have received information regarding the evaluation of their application. Receipt of the application will not be acknowledged.

The application must be received no later than 31 December 2011. Applications received later than this date will not be considered.

Questions

For specific information about the PhD scolarship, please contact

Prof. Kell Mortensen (kell@life.ku.dk );

Associate Prof. Marité Cárdenas Gómez (cardenas@nano.ku.dk ) or

Prof. Dimitrios Stamou (stamou@nano.ku.dk ).

General information about PhD programmes is available at www.LIFE.ku.dk/LIFEphd .

Apply online

Deadline: 31-12-2011

FOR DETAILS, PLEASE REFER http://www.ku.dk/english/available_positions/vip/

Research Assistant post at Faculty of Biological and Environmental Sciences,University of Helsinki

University of Helsinki

POST: Research Assistant

POSITION ANNOUNCED ON: Dec 22, 2011

APPLY AT LATEST ON: Jan 16, 2012 at 3:45 PM

FIXED-TERM: Feb 1, 2012 - Dec 31, 2013

EMPLOYER:Faculty of Biological and Environmental Sciences, Department of Biosciences

The Faculty of Biological and Environmental Sciences / University of Helsinki with its neighboring units form the largest and most prominent scientific and educational unit for life sciences in Finland. The significance of biological and environmental knowledge for the entire society is increasing – applications of biosciences play significant role in health care and medical sciences as well as in answering to environmental questions such as conservation of biodiversity and sustainable use of natural resources. In the Department of Biosciences (major of Physiology and Neuroscience), the research group of University Lecturer, Doc Reijo Käkelä focuses on ecophysiological and biomedical roles of lipids and fatty acids.

Department of Biosciences invites applications for a RESEARCH ASSISTANT

The fixed-term contract begins February 1st, 2012 and expires December 31st, 2013 (duration 23 months). Location: Biocenter 3, Viikinkaari 1, Helsinki.

Research assistant will work in a project ECOSEAL, Baltic seals – balancing between sustainable ecosystem management and fisheries, which is funded by the Central Baltic INTERREG IV A Programme 2007–2013 of European Union. The lead partner of the project is Finnish Game and Fisheries Research Institute and University of Helsinki is one of the several partners located in Finland, Sweden and Estonia. The task of the Käkelä group is to take part in evaluating the ecological role of seals in the Baltic Sea by applying fatty acid biomarkers to study the foraging ecology of the seals. Thus the main task of the researcher assistant is to analyze fatty acid biomarkers in tissues of seals and their potential prey fish in laboratory by using gas chromatography. The data are studied by multivariate statistics (mainly principal component analysis).

The successful applicant will ideally have skills in physiology, biochemistry and ecology and plans for a career of researcher. Earlier experiences in gas chromatography or multivariate statistics will be a plus. Good verbal and written communication skills are essential in English, skills in Finnish and Swedish beneficial but not necessary. However, we encourage you to send an application even if you would not meet all the criteria since the work has to start February 1st and the most suitable applicant by that time will be elected.

The salary will be based on level 1 of the demands level chart for teaching and research personnel in the salary system of Finnish universities. In addition, the appointee will be paid a salary component based on personal performance. he work suits the best to a master student in a late phase of the studies. However, this is NOT a pro gradu-project.

The application should include a complete CV including education, possible degrees obtained and prior work experience; if possible, give the names and contact information for at least one referee. The applications (in English, Finnish or Swedish) should be sent to University Lecturer, Reijo Käkelä, Department of Biosciences / Physiology and Neuroscience, Biocenter 3, room 2712, P.O. Box 65, 00014 UNIVERSITY OF HELSINKI, and they should arrive by 16th of January 2012, 3.45 PM.

For more information please contact Reijo Käkelä, (+358) 9 191 59866, reijo.kakela@helsinki.fi

[unfortunately travelling and out of reach during January 1st–16th; discussions also possible after submitting the application by Jan 16th].

FOR DETAILS, PLEASE REFER http://www.helsinki.fi/recruitment/index.html?id=50619

Postdoctoral fellow position(Transcriptional Regulation in Immune Cells) at NIAID, Bethesda

Transcriptional Regulation in Immune Cells

National Institute of Allergy and Infectious Diseases, Bethesda, MD and surrounding area

A postdoctoral fellow position is immediately available in the Molecular and Cellular Immunoregulation Unit (MCIU) in the Laboratory of Immunology, NIAID. The MCIU aims to address diversity and plasticity of CD4 T helper (Th) subsets, regulation of Th cell fates/functions and the expression of lineage-specific genes by transcription factor complexes, and cellular/molecular requirements for the development of distinct Th subsets. Projects include generation of multi-color "reporter" and fate-mapping murine models to study heterogeneous Th cell populations in autoimmune, allergic and infectious settings, as well as genome wide analyses of gene expression, epigenetic modifications and transcription factor binding in these subsets using RNAseq and ChIPseq technologies. We are also interested in studying transcriptional regulation in other immune cells and human CD4 T cells which may have implications in immune-related human diseases.

We are seeking highly motivated and collaborative individuals capable of independent reasoning and excited about learning new technologies.

REQUIREMENTS:

The candidates must have a Ph.D. or M.D. degree with less than five years of postdoctoral experience. Preference will be given to candidates who have knowledge in immunology, in vivo animal models, human diseases or bioinformatics in high throughput datasets analyses. Previous experience in molecular and cellular biology is essential for the applicants without bioinformatics background. The candidates should have excellent writing and communication skills.

TO APPLY:

Please send a short statement of your research goals, curriculum vitae, bibliography, and names and contact information of three references to Dr. Jeff Zhu jfZhu@niaid.nih.gov  (email preferred) or to the following address:

Jinfang (Jeff) Zhu, Ph. D.

Molecular and Cellular Immunoregulation Unit

Laboratory of Immunology

National Institute of Allergy and Infectious Diseases

National Institutes of Health, DHHS

Building 10, Room 11D02

10 Center Drive

Bethesda, MD 20892-1892

The NIH is dedicated to building a diverse community in its training and employment programs.

FOR DETAILS, PLEASE REFER

https://www.training.nih.gov/postdoc_jobs_nih/view/_31/1041/Transcriptional_Regulation_in_Immune_Cells

Beaufort Senior Research Fellowship at Queen’s university, Belfast

Queen’s university, Belfast

POSITION: Beaufort Senior Research Fellowship

SCHOOL/DEPARTMENT: School of Biological Sciences

REFERENCe: 11/101888

CLOSING DATE: Friday 27 January 2012

SALARY: £37,990 per annum

ANTICIPATED INTERVIEW DATE: February 2012

DURATION: 3.5 years

JOB PURPOSE:

To lead and conduct pioneering research in theoretical marine community ecology of relevance to fisheries management within the Beaufort project-plan and raise the University’s international reputation by taking significant rôles in international fora and publishing high impact papers in relevant journals. Also to contribute significantly to the planning of Beaufort research activities, supervision of

research students and to provide world-class specialist advise to theoretical ecology research projects in the School.

MAJOR DUTIES:

1. Lead scientific innovation by planning and conducting original theoretical research in marine community ecology, leading the subject into new territory through the publication and dissemination of pioneering research so that it can provide a theoretical foundation for ecosystem management of commercial fisheries.

2. Construct and evaluate computer-based models of marine community dynamics in fulfilment of the plans agreed for the Beaufort programme in theoretical ecology for fisheries management.

3. Significantly contribute to planning and development of theory components of Beaufort EAFM through work-plan specification,collaboratively establishing goals for research students, contributing to Beaufort planning meetings and strategic developments and mentoring and advising research students and staff.

4. Initiate and develop grant applications for further funding in marine ecology and fisheries management and make appropriate contributions to their execution (upon success), including the establishment and cultivation of international scientific collaborations.

5. Take a significant role in Beaufort Consortium programme of stake-holder engagement by initiating and taking part in meetings and other communications designed to engage fisheries managers, marine ecosystem management decision makers and other identified stake-holders.

6. Take a significant role in planning for the future continuation of the marine theory research group beyond the Beaufort Grant,

including the preparation of research plans to secure funding for the research group and its lateral extensions. Ensure that research projects are completed on time and within budget.

7. Contribute to the strategic thinking and planning of the theoretical ecology research group and wider Ecology, Evolution, Behaviour and Environmental Economics research cluster, following the School’s Academic Plan, including taking part in the coaching and developing of research staff where appropriate.

8. Manage the use of specialist resources within the research group and contribute to planning and maintenance of computational biology resources for the research group, including assisting in basic system management tasks.

9. Represent the School, the University, and the Beaufort Consortium in international meetings, advisory bodies and scientific publications, to enhance the reputation of the hosting bodies, and to gain wider recognition in the subject field and advance the theory of marine ecosystem management.

PLANNING AND ORGANISING:

1. Plan and organise own work over remaining contract.

2. Lead the supervision of one PhD student and support in supervision of two others.

3. Lead in collaborations and grant development work to extend beyond Beaufort funding.

4. Significantly contribute to annual reports and work-plans.

5. Establish academic priorities within the Beaufort work-plan.

6. Organise scientific communications meetings and significantly contribute to Beaufort stake-holder group meetings and scientific conferences.

7. Act independently in leading research activity, operating within broadly defined research objective over a 3.5-year time-span with significant decision making latitude.

RESOURCE MANAGEMENT RESPONSIBILITIES:

1. Responsible for own working environment and resources and provision of computational services on unix compute-servers.

2. Responsible for day-to-day work of one to two PhD students.

3. Responsible for resource management of own research grants, collaborative enterprises and meeting organisation.

4. Significantly contribute to resource management of those of the School’s bio-theory group and to goal setting for other researchers in the team and collaboration.

5. Act as a mentor for students and Research Fellows.

INTERNAL AND EXTERNAL RELATIONSHIPS:

1. Report to leader of the School bio-theory research group.

2. Direct, advise and motivate research students.

3. Represent the University in international fisheries committee – negotiation and specialist advice.

4. Act as key contact with external funding projects - exchanging information, motivating and negotiating.

5. Take a lead in stake-holder engagement – communicating complex and conceptual ideas at various levels of understanding appropriate to a diverse range of audiences.

essential criteria:

1. A relevant degree with a PhD completed in a mathematical subject (e.g. physics, mathematics, mathematical biology, mathematical computation, computational fisheries science).

2. A high academic standing with a growing reputation in research within theoretical community ecology and / or quantitative fisheries science.

3. A sustained RAE returnable record of peer reviewed journal publications in theoretical or mathematical modelling.

4. Expertise with at least one mathematical modelling language such as Matlab, Mathematica, or R.

5. Experience, achievement and growing reputation in the discipline, reflected in relevant international committee memberships (e.g.ICES) and/or involvement in international research events.

6. Experience of leading the research field in new areas by pioneering creative thinking.

7. Mastery of the subject and ability to lead academic research.

8. Ability to communicate complex information effectively in a wide variety of academic fora and engaging with stake-holders.

9. Supervise research projects of post graduate students.

10. Ability to communicate in English.

11. Ability to manage resources.

12. Demonstrable intellectual ability.

13. Ability to supervise work of others in research team and persuade colleagues and stakeholder groups.

14. The Beaufort Fellowship in EAFM was created to provide a platform for new leadership in marine community ecology relevant to Ecosystem Management.

DESIRABLE CRITERIA:

1. Experience with Unix tools and willingness to learn basic Unix cluster management .

2. Experience of parallel computing for numerical modelling.

FOR DETAILS, PLEASE REFER

https://hrwebapp.qub.ac.uk/tlive_webrecruitment/wrd/run/ETREC107GF.open?VACANCY_ID=4674261eHH&WVID=6273090Lgx&LANG=USA

or https://knock.qub.ac.uk/itrent_web_rec_docs/job_desc/11_101888.pdf

Applications are invited for Dean(Faculty of Environmental Studies) at York University

Faculty of Environmental Studies (FES)

YORK UNIVERSITY

POST: Dean, Faculty of Environmental Studies

Applications and nominations are invited for the position of Dean of the Faculty of Environmental Studies at York University. The appointment is for a five-year term, commencing July 1, 2012.

Founded in 1959, York University offers a world-class, modern, interdisciplinary academic experience in Toronto, Canada’s  most multicultural city. York is at the centre of innovation,with a thriving community of almost 60,000 faculty, staff and students who challenge the ordinary and deliver the unexpected.

The University has 10 faculties, offering over 5,000 courses and degrees at the undergraduate, graduate and doctoral levels. York is Canada’s third-largest university, with over 240,000 alumni, an operating budget of $890 million and over 280 international partnerships

More information is available at http://www.yorku.ca/

The Faculty of Environmental Studies (FES), established in 1968, redefines the conceptual and theoretical boundaries of environmental studies.  Additional information about FES is available

at www.yorku.ca/fes

 The Dean is the chief academic and administrative officer of the Faculty, and leads the Faculty in its teaching, research and service missions, as well as directing its budget, general administration and future development. She or he is an important member of York's senior leadership team, contributing

to the future directions of the University. The successful candidate will bring a strong record of academic and administrative experience and leadership to this position.

York University is an Affirmative Action Employer. The Affirmative Action Program can be found on York’s website at www.yorku.ca/acadjobs/ . All qualified candidates are encouraged to apply.

The search committee will begin reviewing applications in January and will continue until the position is successfully filled. Please respond electronically, in confidence, with a letter of introduction and a curriculum vitae that includes the names of three references (who will not be contacted without the consent of the applicant) to the University’s consultant:

Laverne Smith & Associates Inc.

1 Yonge Street, Suite 1801

Toronto, Ontario M5E 1W7

York@lavernesmith.com

FOR DETAILS, PLEASE REFER

http://webapps.yorku.ca/academichiringviewer/specialads/FES_Dean_Dec_2011.pdf

Assistant Professor (Environmental Biology) vacancy at York University, Canada

York University

Toronto, Ontario, Canada

POSITION RANK: Full Time Tenure Stream - Assistant Professor 

DISCIPLINE/FIELD: Environmental Biology 

HOME FACULTY: Science and Engineering 

HOME DEPARTMENT/AREA/DIVISION: Biology 

AFFILIATION/UNION: YUFA 

POSITION START DATE: July 1, 2012 

The Department of Biology, Faculty of Science & Engineering invites applications for a tenure-track position in the area of Environmental Biology at the Assistant Professor level. The start date is July 1, 2012.

Applications are welcomed from individuals whose proposed research programs compliment and extend existing research activities in the department, particularly (but not limited to) the areas of climate change, invading species, multiple stressors and ecotoxicology. Emphasis for all candidates will be on research excellence.

The successful candidate will have a PhD in Biology or a related field, post-doctoral (or equivalent) experience and an outstanding research record, and will be expected to develop a strong, externally-funded research program, contribute to teaching biology-related courses at the undergraduate and graduate levels and supervise graduate students. The successful candidate must be eligible for prompt appointment to the Faculty of Graduate Studies. Further information about the Department of Biology can be found at http://science.yorku.ca/Schools-Departments/Biology/

All positions at York University are subject to budgetary approval.

York University is an Affirmative Action Employer. The Affirmative Action Program can be found on York's website at www.yorku.ca/acadjobs or a copy can be obtained by calling the affirmative action office at 416-736-5713. All qualified candidates are encouraged to apply; however, Canadian citizens and Permanent Residents will be given priority.

Applications must be received by January 15, 2012. Applicants should forward (in hard copy) a curriculum vitae, an outline of their research plans, single copies of three publications, and arrange for three signed letters of reference to be sent to:

Chair, Environmental Biology Search Committee, Department of Biology, Room 247 Farquharson Building, York University, 4700 Keele St., Toronto, Ontario, Canada, M3J 1P3, Fax: 416-736-5698.

 

FOR DETAILS, PLEASE REFER

http://webapps.yorku.ca/academichiringviewer/viewposition.jsp?positionnumber=1264

Postdoctoral Fellow position(Optogenetic Manipulation of Neuronal Activity in Behaving Mice) at National Institute of Mental Health, Bethesda

Optogenetic Manipulation and/or Multiple Single-unit Recording of Neuronal Activity in Behaving Mice

The National Institute of Mental Health, Bethesda, MD and surrounding area

POST: Postdoctoral Fellow

The National Institute of Mental Health (NIMH), Section on Neural Gene Expression seeks to fill one (1) Postdoctoral Fellow position. Our laboratory explores the roles of oxytocin and vasopressin in learning and behavior in mice. The lab uses a variety of techniques including in situ hybridization, viral delivery of gene expression systems, transgenic, including conditional knockout, mice and behavioral assays. We wish to begin using optogenetic manipulation and/or multiple single-unit recording (e.g., of place cells) of neuronal activity of behaving mice to enhance our investigations. Candidates with a strong background in optogenetics and/or multiple single-unit recording techniques are encouraged to apply.

REQUIREMENTS:

Applicants should have a Ph.D. and/or M.D. degree and a maximum of 4 years of postdoctoral experience.

NIMH is a major research component of the National Institutes of Health and the Department of Health and Human Services, which have nationwide responsibility for improving the health and well being of all Americans.

TO APPLY:

Interested applicants should send curriculum vitae with bibliography, together with three letters of reference to:

W. Scott Young, M.D.,Ph.D.

Chief, Section on Neural Gene Expression, NIMH

9000 Rockville Pike

Building 49, Room 5A56

Bethesda, MD 20892-4483 USA

or e-mail to wsy@mail.nih.gov

Section on Neural Gene Expression, Division of Intramural Research, National Institute of Mental Health

Bethesda, MD

Application Deadline Date: May 31, 2012

This position is subject to a background investigation.

The NIH is dedicated to building a diverse community in its training and employment programs.

FOR DETAILS, PLEASE REFER https://www.training.nih.gov/postdoc_jobs_nih/view/_31/1046/Optogenetic_Manipulation_and/or_Multiple_Single-Unit_Recording_of_Neuronal_Activity_in_Behaving_Mice

Postdoctoral Fellow (Brain Lipids in Neurotransmission and Neuroinflammation) at National Institute on Aging, Bethesda

Brain Lipids in Neurotransmission and Neuroinflammation

National Institute on Aging, Bethesda, MD and surrounding area

POST: Postdoctoral Fellow

A postdoctoral fellowship position is available in the Brain Physiology and Metabolism Section of the National Institute on Aging on the NIH Bethesda campus, to examine brain lipid metabolism in health and disease. Certain brain post-synaptic neuroreceptors and glial cytokine receptors are coupled to activation of phospholipases A2 enzymes, leading to release of the lipid second messengers, arachidonic and docosahexaenoic acid, from membrane phospholipid. In our laboratory, we use different techniques to quantify and modify these brain signaling processes in unanesthetized rodent models: quantitative autoradiography to image lipid signaling following injection of a radiolabeled fatty acid, molecular and activity analyses of relevant brain enzymes and synaptic and neuroinflammatory markers, immunocytohistochemistry, behavioral testing, lipid analytical methods (GC, HPLC), and kinetic modeling. We study rodent models of aging, of human neuropsychiatric disease (HIV-1 transgenic rat, neurotransmitter reuptake transporter, neuroreceptor and enzyme knockouts, APOE transgenic mice, behavioral models of depression and mania) and of neuroinflammation and neuroexcitotoxicity. In these models, we also quantify effects of relevant drugs (mood stabilizers including lithium, antidepressants, antipsychotics, aspirin and other antiinflammatory agents), changes in dietary polyunsaturated fatty acid (PUFA) composition and in liver PUFA metabolism. We try to choose our animal studies for later translation into relevant human subject protocols.

REQUIREMENTS:

The successful candidate will focus his/her efforts on these studies. A background in lipid metabolism and/or neuropharmacology would be appropriate. Requirements include a Ph.D. and/or M.D. with less than 5 years of postdoctoral experience. Fellows are paid according to the NIH Intramural Research and Training Award Schedule for their level of experience.

TO APPLY:

Applications should include a cover letter describing research experience and research interests, Curriculum Vitae, bibliography and three letters of reference including present or past supervisor(s) and sent by E-mail or surface mail to:

Stanley I. Rapoport, M.D. Chief, Brain Physiology and Metabolism Section

National Institute on Aging, National Institutes of Health

Building 9, Room 1S-128, 9000 Rockville Pike

Bethesda, MD 20892

Email: sir@helix.nih.gov

The NIH is dedicated to building a diverse community in its training and employment programs.

FOR DETAILS, PLEASE REFER

https://www.training.nih.gov/postdoc_jobs_nih/view/_31/1045/Brain_Lipids_in_Neurotransmission_and_Neuroinflammation

Postdoctoral Fellow(Molecular and Cellular Imaging) at National Heart, Lung, and Blood Institute, Bethesda

Molecular and Cellular Imaging

National Heart, Lung, and Blood Institute, Bethesda, MD and surrounding area

POST: Postdoctoral Fellow

The laboratory of Justin W. Taraska has openings for postdoctoral positions at the Laboratory of Molecular Biophysics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland. Our research utilizes fluorescence, structural, and imaging tools to understand how membrane proteins and vesicles function at both the molecular and cellular level. Specific proteins of interest include ion channels and proteins involved in membrane trafficking and synaptic transmission.

REQUIREMENTS:

Candidates with strong interests in imaging single proteins and vesicles, fluorescence, protein structure, image processing, and developing biophysical methods for cellular imaging are encouraged to apply. Applicants should have no more than four years of relevant postdoctoral experience.

Appointments and salary are commensurate with research experience, accomplishments and based on NIH guidelines.

TO APPLY:

Applicants should submit a C.V., a brief letter of research interests and career goals, and the names of three references to: justin.taraska@nih.gov

The NIH is dedicated to building a diverse community in its training and employment programs.

FOR DETAILS, PLEASE REFER

https://www.training.nih.gov/postdoc_jobs_nih/view/_31/1044/Postdoctoral_Positions_in_Molecular_and_Cellular_Imaging