Post-Doc opportunities in Molecular Infection Biology/Microbiology and Protein Quality Control in Sweden

Post-Doc opportunities in Molecular Infection Biology/Microbiology and Protein Quality Control

Post-doctoral candidates have the opportunity to apply to post-doctoral fellowships available from Swedish or European funding agencies. They can also compete for funding available in the laboratory. The successful candidate will participate in activities provided by the Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå Centre for Microbial Research (UCMR) at Umeå University and the Nordic EMBL Partnership for Molecular Medicine, thus providing interaction with researchers from different research fields and access to various scientific and technical expertises.

The proposed projects are related to the field of protein quality control (chaperones, proteases) in the Gram-positive bacterial pathogens Listeria monocytogenes and Streptococcus pyogenes.

LOCATION:

Our new lab in Sweden belongs to the MIMS (The Laboratory for Molecular Infection Medicine Sweden (MIMS) within the Nordic EMBL Partnership for Molecular Medicine). MIMS constitutes the Swedish node within the Nordic partnership for Molecular Medicine that is formed together with the European Molecular Biology Laboratory (EMBL) and the Finland and Norway nodes. MIMS is established within the Umeå Centre for Microbial Research (UCMR) at Umeå University. The groups of the MIMS work in modern laboratories with well-equipped common facilities and platforms in a creative, inspiring and highly interactive environment.

APPLICATION PROCESS:

Highly qualified and motivated fellows from all over the world are invited to apply. Applicants must hold or anticipate receiving within the next months a PhD degree in the fields relevant for the position. Applicants should have a high interest in the field of microbiology, RNA and protein biology and be willing to take on a scientific and technical challenge. A strong background in knowledge and techniques of molecular biology, RNA or protein biochemistry and microbiology and excellent English knowledge is highly desirable.

Applicants should send:

• a cover letter
• a brief statement of research experience and interests,
• a CV,
• a list of publications
• three letters of reference (or the names of three referees) to

 Dr. Emmanuelle Charpentier

Email: emmanuelle.charpentier@mims.umu.se

APPLICATION DEADLINE: September 30, 2011

FOR DETAILS, PLEASE REFER

http://www.mims.umu.se/en/jobs/1438-postdoc-opportunities-in-emmanuelle-charpentiers-lab-protein-quality-control.html

Ph. D Position available in Molecular Infection Biology and Microbiology at MIMS , Umea, Sweden

Ph. D Position available in Molecular Infection Biology and Microbiology

A PhD position in Molecular Infection Biology and Microbiology (Small regulatory RNAs, CRISPR, protein quality control in the Gram-positive pathogenic flesh-eating bacterium, Streptococcus pyogenes) is available at the MIMS (Umea University, EMBL affiliation) in the group of

 Dr. Emmanuelle Charpentier (http://www.mims.umu.se/en/groups/emmanuelle-charpentier.html)

PROJECT DETAILS:

The proposed project is embedded into three current topics of the laboratory: small regulatory RNAs, CRISPR and protein quality control in the Gram-positive pathogenic flesh-eating bacterium, Streptococcus pyogenes but also Listeria monocytogenes.

For more details, please contact Dr. Emmanuelle Charpentier:

Email: emmanuelle.charpentier@mims.umu.se.

POSITION DETAILS:

Starting in fall 2011 for a maximum period of 5 years. The successful candidate will participate in activities provided by the Umeå Centre for Microbial Research at Umeå University (http://www.ucmr.umu.se/) and the Nordic EMBL Partnership for Molecular Medicine.

LOCATION:

MIMS (The Laboratory for Molecular Infection Medicine Sweden (MIMS) within the Nordic EMBL Partnership for Molecular Medicine).

APPLICATION PROCESS:

Applicants must hold or anticipate receiving within the next months a University degree equivalent to a European University Master degree. Applicants should have a high interest in the field of molecular infection biology and be willing to take on a scientific and technical challenge. Prior hands-on experience in molecular biology and microbiology and excellent English skills are highly desirable.

Applicants should send a cover letter with a brief statement of research experience and interests, a CV and three letters of reference (or the names of three referees) to

Dr. Emmanuelle Charpentier (emmanuelle.charpentier@mims.umu.se),

 LAST DATE OF APPLICATION: September 30, 2011.

FOR DETAILS, PLEASE REFERwww.mims.umu.se/, www.embl.de/research/partnerships/remote/nordic/index.html,

www.ucmr.umu.se/

http://www.mims.umu.se/en/jobs/1439-phd-position-in-emmanuelle-charpentiers-lab-small-regulatory-rnas-crispr-protein-quality-control.html

Postdoctoral position in transcriptome analysis of innate immune cells at University Hospital, Jena , Germany

Postdoctoral position in transcriptome analysis of innate immune cells

Postdoctoral position in transcriptome analysis of innate immune cells is available in the “Host Septomics” group at the University Hospital Jena headed by Prof. Hortense Slevogt.

START DATE: The tentative start date is November 1st, 2011 or soon thereafter. The position is initially limited until November, 2013 but may be extended depending on funding.

BACKGROUND:

The “Host Septomics” group aims to analyse the cellular responses to an infection with the most common bacterial sepsis pathogens on a molecular level. The group use human primary cell cultures, patient samples and mouse models of infection to establish integrative models linking intracellular signal transduction, genome and transcriptome sequencing and cellular responses to investigate the pathogenesis of sepsis (http://www.septomics.de/).

The position is focused on genome and transcriptome sequencing of next-generation sequencing data, in particular transcriptome analysis. A PhD in a relevant field is required. The ideal candidate should have demonstrated interests and experiences in the analysis of genomic and transcriptomic data, ideally high-throughput sequencing data arising from the Illumina iScanSQ System. In addition, excellent experience with molecular procedures such as isolation of innate immune cells, Real-time PCR gain-of-function and loss-of-function techniques are required. She/he should have a strong background in immunology, molecular and cellular microbiology but other areas of expertise will be considered. Moreover, strong research experience in the analysis of large and diverse datasets and excellent communication skills to work in a multi-disciplinary team are of importance.

QUERIES AND CONTACT TO BE MADE:

For additional questions concerning the project interested person can contact Prof. Dr. Hortense Slevogt (hortense.slevogt@charite.de),

 for questions concerning the application procedure contact the

SEPTOMICS coordination office

Dr. Janina Hahn,

Email:  septomics@hki-jena.de

Tel: 0049-3641-532-1374

Salary is paid according to German TV-L depending on the applicant’s qualification. The University Hospital Jena is an equal opportunity employer and welcomes applications from all sections of the community. Among candidates of equal aptitude and qualification handicapped persons will be given preference. Moreover, the University Hospital is committed to increase the percentage of female scientists and therefore especially encourages them to apply.

Interested candidates should submit a cover letter describing their research accomplishments and career goals as well as CV, copies of certificates, publication list and contact information for three references. Complete applications (one single pdf-file) should be submitted before October 15th, 2011 to

septomics@hki-jena.de

FOR DETAILS, PLEASE REFER

http://www.hki-jena.de/index.php/43de214fb9e88bf40b2f166b63298285/2/358/download/3262

Postdoctoral positions in “Fungal Septomics”, Germany

Postdoctoral positions in “Fungal Septomics”

The Centre for Innovation Competence (CIC) SEPTOMICS is a research centre of the Friedrich-Schiller-University Jena, the Jena University Hospital and the Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knoell-Institute - funded by the German Federal Ministry of Education and Research. SEPTOMICS research focus lies on the pathogenesis and the pathophysiology of sepsis. As a unique centre for integrated sepsis research SEPTOMICS combines state-of-the-art interdisciplinary fundamental research on sepsis pathogens and the associated host response with cutting-edge clinical expertise in order to develop an improved holistic model of sepsis. Such a model is indispensable for the development of new, badly needed, life-saving sepsis diagnostics and biopharmaceuticals (http://www.septomics.de/).

Starting from October 15, 2011 SEPTOMICS offers a position as Scientific Assistant (PostDoc, 40hrs/week, TV-L E13) in the research group “Fungal Septomics“ (Head Prof. Dr. Oliver Kurzai).

The group analyses the pathophysiology of systemic mycoses. The working spectrum comprises fundamental infection biology as well as clinically oriented questions. The main focus of the applicants research will be the characterization of the interaction of human pathogenic fungi with human immune cells.

The recruiter expects a natural science university degree with a completed PhD, outstanding general knowledge and a good proficiency in German and English. Practical experiences in immunological and/or cell biological techniques are of advantage, although this position is also suited for candidates that recently finished their PhD. Apart from the scientific work your tasks will also include the supervision of master, diploma and PhD students.

The position offers a challenging and diversified position in a fascinating interdisciplinary research field at the interface between fundamental research and clinical application. The selected candidate will be part of a young and dynamic team of international scientists and work in a modern, excellently equipped laboratory. If the candidate have any questions concerning the project,

Please Contact:

 Prof. Dr. Oliver Kurzai

Email: oliver.kurzai@hki-jena.de

Tel.: 03641/5321347

For general questions concerning the application, please contact

SEPTOMICS Head Office

Dr. Janina Hahn,

Email: septomics@hki-jena.de

Tel.: 03641/5321374

Salary is paid according to German TV-L depending on the applicant’s qualification. The contract is initially limited to one year, an extension is possible. The Friedrich-Schiller-University Jena is an equal opportunity employer and welcomes applications from all sections of the community. Among candidates of equal aptitude and qualification handicapped persons will be given preference. Moreover, the Friedrich-Schiller-University Jena is committed to increase the percentage of female scientists and therefore especially encourages them to apply.

Interested candidates should submit their complete application (one single pdf-file) including all necessary documents (letter of motivation, curriculum vitae, examination certificates, publication list, references) before September 28, 2011 to

septomics@hki-jena.de

FOR DETAILS, PLEASE REFER

http://www.hki-jena.de/index.php/43de214fb9e88bf40b2f166b63298285/2/358/download/3263

Group Leader (Infection Immunobiology) at HKI, Germany

JOB ADVERTISEMENT NO. 135/2011

POST: GROUP LEADER (INFECTION IMMUNOBIOLOGY)

v  The Friedrich Schiller University, Jena and the Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI)– are establishing a joined Junior Research Group Infection Immunobiology and invite applications for the group leader position. Research in the group should focus on the interaction of immune effector cells with human-pathogenic fungi or on related questions of cellular infection immunobiology.

v  Thorough knowledge of RNAi manipulation of host cells is expected in order to elucidate the significance of host specific factors in infection defense. Participation in the graduate schools in Jena such as ILRS, JSMC and other collaborative research programmes on the infection biology of human-pathogenic fungi is desired.

v  We are seeking an excellent, highly motivated scientist with a PhD in biology, biochemistry or the life sciences. Comprehensive experience with modern laboratory methods in immunobiology, molecular biology, cell biology and various “omics” technologies as well as a good command of the English language is required.

v  International experience (e.g. as postdoc) is advantageous. The junior research group is structurally integrated into the Friedrich Schiller University Jena (FSU) and situated at the Hans Knöll Institute (HKI) as an independent research unit. Funding for personnel, equipment and consumables will be provided for a period of five years.

v  The full-time position is available for a period of five years. After two years, an intermediary evaluation will be carried out. Salary will be paid up to salary group 15 according to the regulations of the salary agreement for public service employees (TV-L) depending on the applicant’s personal qualifications.

v  We are aiming to increase the percentage of female scientists and particularly encourage qualified female candidates to apply. FSU and HKI are equal opportunity employers.

For further information please contact:

Prof. Dr. Axel Brakhage

Ph:+49 (0)3641 532 1001

Email: axel.brakhage@hki-jena.de

Complete applications include a research plan, CV, and a list of three potential referees.

APPLICATION DEADLINE:  October 31, 2011.

Please refer to job posting No. 135/2011 when submitting to:

anja.wahlmann@uni-jena.de

MAIL ADDRESS: Friedrich-Schiller-Universität Jena Dezernat für Personalangelegenheiten Sachgebiet Wissenschaftliche Beschäftigte Fürstengraben 1 07743 Jena Germany

FOR DETAILS, PLEASE REFER

http://www.hki-jena.de/index.php/43de214fb9e88bf40b2f166b63298285/2/358/download/3265

Postdoctoral Positions in epigenetic research in The Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany

Postdoctoral Positions in epigenetic research

Date: 05.08.2011

Research Group: Prof. Dr. Thomas Jenuwein

Contact person: Ms. Weigold, The Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany.

All positions are available in the Department of Epigenetics (head: Thomas Jenuwein) and are for an initial two-year appointment with the possibility of extension. The Jenuwein group is part of the newly established Epigenetic Focus, which currently comprises two senior groups (Akhtar, Jenuwein) and 3 junior groups (Pichler, Pospisilik, Schneider). This epigenetic hub also extends to colleagues from other departments and will be expanded by at least two junior groups. Together, it represents one of the centers for epigenetic research in Germany. Research at the MPI is supported by a strong institutional infrastructure and several service units such as mass-spectrometry, bioinformatics, Solexa-sequencing for genome-wide analyses, high-end imaging and FACS sorting. The MPI of Immunobiology and Epigenetics is an international research institute and the working language is English.

The Jenuwein group studies the basic composition of mammalian heterochromatin. Approaches used include the biochemical definition of histone lysine methyltransferases, mass-spectrometry of histone modifications and genome-wide chromatin profiling (including deep-sequencing), the functional dissection of non-coding RNAs, the generation of mouse mutants, the analysis of chromatin signaling pathways (e.g. stress response) and overall chromosome structure.

For more information, please go to:

http://www.immunbio.mpg.de/research-groups/epigenetics/laboratory-thomas-jenuwein/

Highly motivated and experienced postdoctoral fellows are required for the following projects:

(1) Dissection of signalling pathways to heterochromatin

(2) Chemistry and screening for small molecule inhibitors

(3) Identification of novel Su(var) genes in both Drosophila (collaboration with Prof.  G. Reuter, Halle/S.) and mouse

(4) Bioinformatics analysis of genome-wide data sets (ChIP-seq, RNA-seq)

Candidates interested in these positions should have a solid background in molecular biology, cell biology, biochemistry or bioinformatics. Additional experience in either chromatin-related techniques, analysis of signaling pathways, high-throughput screens, organic chemistry or Drosophila/mouse genetics will be plus. Candidates should have first-author publications in leading journals and be able to successfully apply for independent fellowships within the next two years.

Salaries will be according to postdoctoral fellowships of the Max-Planck Society. A childcare facility is directly attached to the MPI of Immunobiology and Epigenetics. Women are especially encouraged to apply; handicapped applicants with equal qualifications will be given preferential treatment.

HOW TO APPLY: Candidates should send their application:

Comprising C.V.,

Publication list,

A 1-page research proposal and

Names of three referees indicating the reference number 010811

All these to be submitted directly via E-mail to Ms. Weigold at weigold@ie-freiburg.mpg.de

 or to the Max Planck Institute of Immunobiology and Epigenetics, Personnel Department, Stübeweg 51, 79108 Freiburg.

Informal inquiries can be directed to Thomas Jenuwein (Tel: +49-761-5108-574;

E-mail: jenuwein@ie-freiburg.mpg.de

LAST DATE OF APPLICATION: 30.09.11

FOR DETAILS, PLEASE REFER  

http://www3.ie-freiburg.mpg.de/jobs/postdoctoral-positions-in-epigenetic-research/

Postdoctoral fellow (f/m) for biological image-based high-content screening, Germany

Postdoctoral fellow (f/m) for biological image-based high-content screening on cell non-autonomous protein aggregate induction – (Code 1067/2011/1)

The DZNE is a center of excellence within the Helmholtz Association that performs translational research on Neurodegenerative Diseases. The center includes eight high-performing sites in Bonn, Dresden, Goettingen, Magdeburg, Munich, Rostock/Greifswald, Tuebingen and Witten. 

Our laboratory studies basic mechanisms of prion formation and transmission. We are especially interested in cell non-autonomous aggregate induction, a mechanism of aggregate formation that might also be of importance to other neurodegenerative diseases such as Parkinson’s disease (Krammer et al., Prion 2009; Krammer et al., PNAS 2009).  To unravel basic mechanisms of intercellular protein aggregate transmission and spreading, we will perform automated cell-based RNA interference and small molecule screens.   

We are looking for a postdoctoral fellow with excellent analytical and organizational skills and a strong interest in automated high resolution microscopy and image analysis. The successful applicant should hold a Ph.D. in cell biology, biotechnology, biochemistry, bioinformatics or related fields. Hands-on experience with liquid handling workstations, liquid dispensers, plate readers and automation scheduling software is preferred. Experience in cell-based screening assays, ideally in high-content screening and image analysis would be an advantage. The candidate should be able to work independently and have excellent team working skills. The candidate will very closely collaborate with the DZNE facilities, Laboratory Automation Technologies“ and „Image Data Analysis“ and with collaborators within the Helmholtz Association. Fluency in English is required. The DZNE Bonn offers a cutting-edge infrastructure, an international environment and excellent working conditions.  

Employment, payment and social benefits are determined by the Public Sector Collective Agreement (Tarifvertrag für den öffentlichen Dienst – TvöD). The job location is Bonn. The position is available immediately for 2 years with the possibility of an extension. The DZNE seeks to increase the number of female personnel in those areas where they are underrepresented and therefore explicitly encourages women to apply. The DZNE is committed to employing more disabled individuals and especially encourages them to apply.

Interested candidates should send their applications including a CV, a list of publications, a summary of research interests and names and contact details of three referees to Christina Graf, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V., Holbeinstraße 13-15, 53175 Bonn or as a single file to application@dzne.de

 For further details please contact Dr. Ina Vorberg at ina.vorberg@dzne.de or by phone (+49 228 43302-560).

TIME LIMIT: 30.09.2011

PLACE: Standort Bonn

CONTACT: Dr. Ina Vorberg

Email: ina.vorberg@dzne.de

FOR DETAILS, PLEASE REFER http://www.dzne.de/?id=196&tx_snjobs_pi1[showUid]=235&L=1