WELLCOME TRUST SANGER INSTITUTE
POST: Postdoctoral Research Fellow (Parasitic helminth genomics)
SALARY RANGE: £28280 to £34778 dependent on experience.
CLOSING DATE: 22nd January 2012
Wellcome trust Sanger institute is seeking to recruit enthusiastic and ambitious postdoctoral fellows in three areas:
DESCRIPTION:
POSTDOCTORAL FELLOW - PARASITIC HELMINTH GENOMICS
You will contribute to a range of projects involving the application of very-high-throughput sequencing technologies to understand the biology of helminths. Existing projects build on genome sequence data to address scientific questions that span from population genomics through to functional genomics and immunology, and include working on a range of nematodes, flukes and tapeworms in collaboration with external experts in particular systems. Key aspects of this role will include the analysis of ‘next generation sequencing’ data, genome assembly and comparison, phylogenetics, population genetics, and analyzing transcriptome data, with the exact mix of projects and approaches depending on the interests and expertise of the successful candidate.
POSTDOCTORAL FELLOW - PARASITE FUNCTIONAL GENOMICS
You will develop functional genomics projects across neglected parasite species. A major focus will be the analysis of gene expression throughout the life cycle of African trypanosomes. Using whole transcriptome sequencing (RNAseq), you will explore differences across the life cycle, for instance between bloodstream and late stage (central nervous system) forms. You will need to be an excellent communicator and work effectively with collaborators. Key aspects of this role will include the analysis of ‘next generation sequencing’ data, especially transcriptome data. The role may involve some lab work depending on the interests and expertise of the successful candidate.
POSTDOCTORAL FELLOW - HELMINTH GENOMICS R&D
You will develop challenging new methodology to exploit sequencing approaches to investigating genome function for parasitic helminths. Key areas will include genome sequencing from small, precious or unusual samples, and developing novel functional genomics approaches. This position will be laboratory-based, working in the context of the spectrum of the Sanger Institute’s R&D activities.
ESSENTIAL SKILLS
For the computer based role(s) you will need to have a PhD and either a strong background in bioinformatics, or a strong background in biology (especially parasitology) matched with some experience in bioinformatics, including simple scripting (e.g. Perl/Python) and statistical analyses (e.g. R package). For the lab based role, you will need to have a PhD and a strong background in molecular biology, ideally with experience using next generation sequencing based approaches. Familiarity with parasitology would be beneficial.
OTHER INFORMATION
Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training.
Successful applicant(s) who have submitted their PhD thesis and are awaiting their PhD award to be confirmed will be placed on a transitional pay point, currently £26103. On confirmation applicants will be moved on to the pay scale above
The Wellcome Trust funded positions are offered on a 3-year contract, starting early 2012.
FOR DETAILS, PLEASE REFER
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