Researcher(Molecular Biology) at IRRI, Philippines

INTERNATIONAL RICE RESEARCH INSTITUTE

POST: Researcher - Molecular Biology (PRS-2012-64-SH)

APPLY BY: 30 May-2012

LOCATION: Philippines

SPECIALIZATION/SKILLS: Profound understanding of molecular biology/genetics with extended hands-on experience in basic molecular techniques (DNA and RNA extraction, PCR and RT-PCR), as well as sequence analyses tools; excellent English and communication skills are required, as well as computer and data analysis skills. This positions includes field work and experience in growing of rice or other crops is highly desirable.

BASIC PURPOSE: The successful candidate will work on the identification and molecular characterization of genes and pathways relevant for the development of rice with tolerance of high temperature stress. This three-year BMZ funded project is part of IRRI’s international and multi-disciplinary effort to develop rice adapted to climate-change.

ROLES AND RESPONSIBILITIES: 1. Study the effect of high temperature and other stresses on the structure of the rice panicle and total spikelet number (reproductive meristem development) in field and controlled-environment conditions. 30%

2. Conduct microscopic analysis of panicle development and apply different staining techniques. 30%

3. Collect samples for molecular analysis and assist PhD student in identifying genes and pathways involved in panicle development and stress tolerance. 30%

4. Assist in other activities needed to achieve the objectives of the project.10%

QUALIFICATION REQUIREMENTS:

BSc degree in physiology, molecular biology/genetics, biochemistry, or related field

Preferably (3) years with laboratory experience

FOR DETAILS, PLEASE REFER

https://recruit.zoho.com/ats/EmbedIndResult.hr?jodigest=HFgMcP5.JMbi9gdx2Ay4HP*0R9XArN3jwKFhSIkLjK7oIj.jHBiRe..XFk2.qf5A&bgrndcolor=66CC66&font=Arial&headercolor=000000&embedsource=Embed

Assistant Scientist(Quantitative Genetics) vacancy at IRRI, Philippines

International Rice Research Institute

POST:Assistant Scientist - Quantitative Genetics (PRS-2012-96-GY)

APPLY BY:30 May-2012

LOCATION: Philippines

SPECIALIZATION/SKILLS: Proficiency in statistical programming (i.e R, SAS) and system maintenance; Ability to understand consultee's problems and make suggestions for appropriate solutions, ability in training scientists and researchers on quantitativr genetics/statistical concepts and theories and their applications to agricultural research; Ability to acquire and learn new methods and techniques through self-study, good interpersonal and human realtion skills, good oral and written communication skills.

BASIC PURPOSE :Provide quantitative genetics advice and assistance to all IRRI researchers and collaborators from other institutions

Develop training materials and delivers of qualitative genetic training to IRRI staff and researchers from collaborating institutions.

Conduct basic quantitative genetics analyses including linkage and association mapping.

Test analytical pipelines/packages for quantitative genetics analysis

ROLES AND RESPONSIBILITIES: 1. Consulting (30%)

Provides technical assistance and works closely with scientists and researchers, from within and outside IRRI, in all aspects of genetic design, analysis, and interpretation to ensure statiscally valid and sound research results.

 Develops R subscripts for non-routine genetic analyses to give researcher access to efficient and reliable analytical methods.

2. Training and Development of Courseware Materials (30%)

Design training courses and develops training materials (i.e., handouts, exercise and, slides)

Acts as resource person and delivers training in in-house and in-country training programs for NARS scientists

3. Testing analytical pipelines/packages for genetic analysis (30%)

Develops testing cases for testing the analytical pipelines/packages for qualitative genetics analysis

Conducts testing and prepare reports

4. Conducting other duties nay be assigned from time to time by supervisors. (10%)

QUALIFICATION REQUIREMENTS

BS in Plant/Animal Qualitative Genetics or Biometrics

At least 3 years experience in plant/animal genetic analysis or related areas

Knowledge of classical and modern genetic analysis methods.

FOR DETAILS, PLEASE REFER

https://recruit.zoho.com/ats/EmbedIndResult.hr?jodigest=HFgMcP5.JMbi9gdx2Ay4HP*0R9XArN3jwKFhSIkLjK7oIj.jHBiRe0bEoD01Ywj.&bgrndcolor=66CC66&font=Arial&headercolor=000000&embedsource=Embed

Specialist - Bioinformatics/Curator at IRRI, Philippines

International Rice Research Institute

POST: Specialist - Bioinformatics/Curator (PRS-2012-91-RM)

APPLY BY: 25 May-2012

LOCATION: Philippines

SPECIALIZATION/SKILLS: Biological Sciences with specialization in molecular biology, genetics, genomics, or biochemistry; or BS or MS degree in Computer Science/Information Technology, with formal credits in genetics/biochemistry or a bioinformatics training certificate from a reputable online training resource (e.g. Bioinformatics.org)

BASIC PURPOSE: The successful candidate will perform bioinformatic anaylses on genomic and multi-omics data generated by IRRI scientists and international collaborators, to curate and annotate rice genomic data and results from analyses, and to assist in bioinformatics capacity building (training) activities at IRRI.

ROLES AND RESPONSIBILITIES: • Perform bioinformatic analyses (using established algorithms/software/pipelines) on genomic and multi-omics data generated by IRRI scientists and international collaborators.

• Curate and annotate rice genomic data and results from analyses.

Out puts of 1 and 2 may include sequence assemblied and curated public on-line repositories of genes/genomes hosted by IRRI

• Compile and help develop bioinformatic training materials, assist in bioinformatics training courses and the use of bioinformatics resources at IRRI.

• Perform all other related bioinformatics duties that may be assigned from time to time by the supervisor(s).

QUALIFICATION REQUIREMENTS

• BS degree in Biological Sciences with specialization in molecular biology, genetics, genomics, or biochemistry; or BS or MS degree in Computer Science/Information Technology, with formal credits in genetics/biochemistry or a bioinformatics training certificate from a reputable online training resource (e.g. Bioinformatics.org)

• Hands-on experience with open source bioinformatics analysis software tools, both standalone and web-based (e.g. BLAST, EMBOSS, GMOD). Experience with gene/genome assembly and annotation is an advantage.

• Capability in using software (with GUI or command-line) under Windows and Linux/Unix operating systems, ability to set-up workflows/pipeline processes for standard analytical tasks.

• Self motivated learner, pro-active, team player with good training and organizational skills

FOR DETAILS, PLEASE REFER

https://recruit.zoho.com/ats/EmbedIndResult.hr?jodigest=HFgMcP5.JMbi9gdx2Ay4HP*0R9XArN3jwKFhSIkLjK7oIj.jHBiRew2Pn9UDdXst&bgrndcolor=66CC66&font=Arial&headercolor=000000&embedsource=Embed

Laboratory Research Assistant post at IRRI, Philippines

International Rice Research Institute

POST: Professional Service (Laboratory Research Assistant)

APPLY BY: 25 May-2012

LOCATION: Philippines

SPECIALIZATION/SKILLS: With skills in conducting analytical tasks and sample processing/preparation in a chemical laboratory. Ability to work with a team in multi-cultural environment. Utmost rigor.

BASIC PURPOSE: The successful candidate will assist in developing and implementing analytical methodologies for rice phenotyping for non-structural carbohydrates and antioxidants.

ROLES AND RESPONSIBILITIES:

 1. Assist in developing sample processing and homogeneity control for Near Infrared Spectrometry (NIR) based analyses of soluble and insoluble sugars in rice plant tissue, in collaboration with ASL;

2. Assist in developing high throughput sampling and analysis methods of natural antioxidants in rice plant tissue using the ORAC assay (fluorescence spectroscopy on microplates);

3. Perform all other related duties that may be assigned from time to time by the supervisor.

QUALIFICATION REQUIREMENT:

• College graduate in a field related to organic chemistry, agricultural chemistry or molecular biology

• At least 1 year laboratory experience

FOR DETAILS, PLEASE REFER https://recruit.zoho.com/ats/EmbedIndResult.hr?jodigest=HFgMcP5.JMbi9gdx2Ay4HP*0R9XArN3jwKFhSIkLjK7oIj.jHBiRe*w9DQMQZX4x&bgrndcolor=66CC66&font=Arial&headercolor=000000&embedsource=Embed

Researcher - Environmental Science at IRRI, Philippines

International Rice Research Institute

POST: Researcher - Environmental Science (PRS-2012-70-RL)

TYPE: Fixed-term, National Posted on 16 May-2012

Apply by 30 May-2012

LOCATION: Philippines

SPECIALIZATION/SKILLS: Excellent communication (oral & written) skills, good technical/ scientific writing skills will be an advantage, ability to work independently, with the minimum supervision, excellent oral and written communication skills.

BASIC PURPOSE: Under the supervision of the Philippine Country Coordinator, the Researcher will implement activities related to the documentation and comparative assessment of past and current local adaptive strategies and coping responses of local communities in Southeast Asian watersheds.

ROLES AND RESPONSIBILITIES: 1. Synthesize available information on local adaptive strategies and coping responses of small holder farmers in Philippine watershed

2. Assess local adaptive strategies and coping responses of small holder farmers in target watersheds through conduct of interview and focus group discussion

3. Assess the role of trees and agroforestry in enhancing the resilience of small holder farmers in SE Asian watersheds

4. Write at least two journal articles based on the research outputs of the project

5. Design and conduct training on appropriate agroforestry systems for climate change adaptation.

6. Assist in the preparation of progress and final reports of the project

7. Perform all other related duties that may be assigned from the time to time by the Country Coordinator

QUALIFICATION REQUIREMENTS:

College degree in Environmental Science, Natural Resource Management, Economics and related fields. Master degree is an advantage

At least 2 years experience

FOR DETAILS, PLEASE REFER

https://recruit.zoho.com/ats/EmbedIndResult.hr?jodigest=HFgMcP5.JMbi9gdx2Ay4HP*0R9XArN3jwKFhSIkLjK7oIj.jHBiRe1Q1rWavawSi&bgrndcolor=66CC66&font=Arial&headercolor=000000&embedsource=Embed

Senior Bioinformatician position at Wellcome Trust Sanger Institute

Wellcome Trust Sanger Institute

CURRENT JOB TITLE: Senior Bioinformatician

ROLE PROFILE REFERENCE: 145/13

GRADE: 4

REPORTS TO [JOB TITLE]:

Vertebrate Resequencing Informatics team leader

TEAM NO: 145

JOB FAMILY: Informatics

MANAGEMENT RESPONSIBILITY FOR: None

ROLE PURPOSE AND PRIMARY OBJECTIVE: To develop a system to process, update, store, and regularly release large sets of human variation calls across large numbers of human genomes.

CORE ACCOUNTABILITIES [IN APPROXIMATE ORDER OF IMPORTANCE TO ROLE PURPOSE]:

To develop a system to process, store and regularly internally release large sets of human variation calls

2. Work with human genetics researchers to make the data available in a format that is convenient to query and analyse

3. To document all code produced and procedures for maintaining and operating the system developed so that other members of the team can operate the system if required

4. Initiate and contribute to problem-solving discussions with the team to generate novel ideas and help the team move forward

5. Plan and carry out own work on daily and weekly timescales

DESCRIBE THE MOST COMPLEX/CHALLENGING ASPECTS OF THE ROLE:

Next generation sequencing technologies are constantly evolving in terms of the type and volume of the sequence data they produce. In the coming years, the vertebrate resequencing informatics group will be managing some of the largest sequencing projects in the world and therefore need to design scalable and robust informatics solutions (data tracking, storage, and computing power). One of the most challenging aspects of this role will be to produce high-quality scientific data on a large scale while adapting to rapid developments in sequencing hardware and software.

KNOWLEDGE, SKILLS AND EXPERIENCE REQUIRED: E = ESSENTIAL D = DESIRABLE

● Significant programming experience in one or more modern programming languages (e.g. Perl, Python, Java etc.) (E)

● Experience of object orientated development (E)

● A high level of communication skills to be able to elicit complex requirements from, and convey complex information to, groups with different levels of technical knowledge (E)

● Ability to quickly adapt to new problems and ideas (E)

● Excellent problem-solving skills (E)

● Some knowledge or experience in bioinformatics (D)

● Experience with managing large volumes of data (D)

● Experience with running software on a compute farm or cluster (D)

● Experience with new sequencing technology data (D)

● Relational database design and manipulation via SQL (D)

INTERACTS WITH:

WHO (TEAMS/PEOPLE/ORGANISATIONS)

Other group members of Vertebrate Resequencing Informatics team

WTSI Human genetics research groups

WTSI Sequencing Production Teams

Internal/external developers of methods and software for variant calling

PURPOSE OF THE INTERACTION

Collaborate on design and development of large scale genotype processing and tracking system

Schedule and announce frozen data releases in a format suitable for researchers to access and use in their experiments

Collaborate on accessing sequencing data to be processed and variants catalogued in the tracking system

Maintain contact with internal and external collaborators to keep up to date with changes and updates in genotyping software

FOR DETAILS, PLEASE REFER

 https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=147972

Bioinformatician post at Wellcome Trust Sanger Institute

Wellcome Trust Sanger Institute

ROLE PROFILE

CURRENT JOB TITLE: Bioinformatician

ROLE PROFILE REFERENCE[FOR HR USE ONLY] : 120/13

GRADE: 5

REPORTS TO [JOB TITLE]: Senior Staff Scientist

TEAM NO: 120

MANAGEMENT RESPONSIBILITY FOR: None

ROLE PURPOSE AND PRIMARY OBJECTIVE:

To assist in the development and production of TreeFam; in close collaboration with Ensembl Compara team as well as world-leading protein and RNA family resources (Pfam, MEROPS and Rfam). Develop and test new features and algorithms, integrate them into the existing TreeFam pipeline and maintain the code base.

CORE ACCOUNTABILITIES [IN APPROXIMATE ORDER OF IMPORTANCE TO ROLE PURPOSE]:

1. Development of TreeFam database resources (code pipeline + website).

2. Develop new features in the databases by incorporating new or extending existing data sources/features.

3. Produce scripts (written in Perl) that integrate with group code base to perform various tasks from data analysis to data entry and integrity, thereby allowing human time to be used more efficiently.

4. Liaise with external databases to ensure successful co-ordination and integration of data, and act upon feedback when appropriate.

5. Plan own work on a daily and weekly basis to ensure that production and research goals are achieved in a timely fashion.

6. Contribute to publication of the research output of the group as guided by line manager.

7. Communicate with the user community to deal with queries that arise from the use of the data provided as well as incorporate data submissions from users.

DESCRIBE THE MOST COMPLEX/CHALLENGING ASPECTS OF THE ROLE

Balancing the need for high productivity with the requirements for high accuracy.

Knowledge, skills and experience required: E = Essential D = Desirable

·         Degree in computer science/bioinformatics (E)

·         MSc or equivalent (D)

·         Computer literacy (linux experience) (E)

·         Good attention to detail (E)

·         Experience of handling large scale biological datasets and utilising scientific databases (D)

·         Good communication/team player skills (E)

·         Problem solving skills (D)

·         Advanced programming skills in Perl and MySQL (D)

·         Time management skills (D)

INTERACTS WITH:WHO (TEAMS/PEOPLE/ORGANISATIONS):

Line manager

Other members of team

External databases

User community

PURPOSE OF THE INTERACTION

Report to/get direction from

Give/obtain advice, keep informed on tasks

Provide information/data

Answering queries

FOR DETAILS, PLEASE REFER https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=148530

Research Assistant( Microbiological phenotyping of mutant mice) at Wellcome Trust Sanger Institute

Wellcome Trust Sanger Institute

ROLE PROFILE

CURRENT JOB TITLE: Research Assistant – Microbiological phenotyping of mutant mice

ROLE PROFILE REFERENCE: 131-09

GRADE: 6

REPORTS TO [JOB TITLE]: Senior Staff Scientist

TEAM NO: 131

JOB FAMILY: Research Assistant

MANAGEMENT RESPONSIBILITY FOR:No-one

INTERACTS WITH:

WHO (TEAMS/PEOPLE/ORGANISATIONS)

Internal Institute teams (mouse genetics, phenotyping)

Pathogen screening and rodent malaria groups

PURPOSE OF THE INTERACTION

Resource, problem solving, and information exchange

Work organisation and scheduling

Role purpose and primary objective:

Microbiological phenotyping of mutant mice generated as part of the wider Sanger Mouse Genetics Programme.

CORE ACCOUNTABILITIES [IN APPROXIMATE ORDER OF IMPORTANCE TO ROLE PURPOSE]:

1.       Conduct laboratory procedures as instructed by supervisor, in line with SOPs to achieve scientific outcomes for use both within and outside of the group.

2.       Collect and understand data and maintain accurate records such that work can subsequently be followed up, reported or interrogated.

3.       Interrogate appropriate database user interface to collate information necessary to carry out work.

4.       Follow good housekeeping and health and safety guidelines to ensure a clean and safe working environment referring issues/problems to area safety supervisor and line manager.

5.       Seek clarification and answers on day to day issues from senior staff members to ensure continuity of work.

6.       Develop and envisage new ways for the work to be more effective and efficient for smooth running and output improvement

DESCRIBE THE MOST COMPLEX/CHALLENGING ASPECTS OF THE ROLE

Effective task management to ensure all tasks are completed to high quality in the agreed timeframe

Handling and processing of large amounts of complex data.

Knowledge, skills and experience required: E = Essential D = Desirable

Undergraduate degree or HND/HNC or equivalent ( E)

Previous laboratory experience including good laboratory practice (E)

Effective team worker and communicator (E)

Effective and organised task manager (E)

Capable use of computers and ability to adapt to new packages (E)

Ability to perform repetitive tasks consistently and confidently (E)

Good level of numeracy and literacy (E)

Scientific knowledge of microbiology gained through experience or formal training (D)

Knowledge of PC packages i.e. Excel, internet usage (D)

Personal license holder (D)

Experience in animal procedures will be an advantage (D)

FOR DETAILS, PLEASE REFER

https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=148190

Postdoctoral Fellow(Identifying mouse genes that modulate malaria) at Sanger Institute

Sanger Institute

POST:Postdoctoral Fellow - Identifying mouse genes that modulate malaria

SALARY: from £28,563 to £35,126  per annum dependent on experience.

CLOSING DATE FOR APPLICATIONS : 22nd May 2012

The Malaria Programme at the Sanger Institute combines natural and experimental genetic approaches to understand fundamental aspects of parasite biology and pathogen-host interactions in malaria. We are particularly interested to identify host genes that control the susceptibility, pathology and immunity to a malaria infection. To this end we interact closely with the mouse genetics project at the Institute, which systematically generates and comprehensively phenotype hundreds of mouse knock out lines each year. As part of this project we have established a panel of functional screens, which use Plasmodium berghei, a malaria parasite infecting rodents, to systematically identify mouse genes that impact on erythrocyte infection, immunopathology and liver stage development. To follow up on hit from our screen, we are now looking for an enthusiastic, independent and broad thinking individual, who will select mouse mutants with interesting phenotypes from our functional screens, and who will develop research projects that will lead to a deep understanding of novel aspects of host-parasite interactions. You will also oversee and further develop our on-going screening activities and work closely with a number of external collaborators. This project provides a unique opportunity to developing innovative research projects at the interface between large research programmes on mouse genetics and pathogen biology

FOR DETAILS, PLEASE REFER

 https://jobs.sanger.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=1764&p_web_page_id=147475